The Contribution of Hepatic Triglyceride Lipase to Plasma Post-Heparin Lipolytic Activity in the Rat

Horm Metab Res 1977; 9(1): 63-65
DOI: 10.1055/s-0028-1093585

Originals

R. S. Elkeles , J. Hambley , D. Bird

Division of Clinical Investigation, Clinical Research Centre and Northwick Park Hospital, Harrow, U.K.

Abstract

Plasma post-heparin lipolytic activity (PHLA) was reduced by 50% in functionally hepatectomised compared with sham-operated rats.

Inhibition of PHLA by protamine sulphate was significantly increased in functionally hepatectomised compared with sham-operated rats.

Hepatic triglyceride lipase contributes significantly to total plasma PHLA. Its function is not yet clear.

Plasma Post-Heparin Lipolytic Activity - Hepatic Triglyceride Lipase - Very Low Density Lipoprotein